| Module Code: CHE2030 |
Module Title: INTERMEDIATE ANALYTICAL CHEMISTRY |
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Module Provider: Chemical Sciences
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Short Name: CHE2030
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Level: HE2
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Module Co-ordinator: WARD NI Prof (Chem Science)
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Number of credits: 15
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Number of ECTS credits: 7.5
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| Module Availability |
| Semester One |
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| Assessment Pattern |
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Coursework/practicals 30%
Multiple Choice/Short answer test /Written Exam 70% |
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| Module Overview |
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| Prerequisites/Co-requisites |
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| Module Aims |
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· To describe and evaluate the fundamentals of modern instrumental methods, including GC and HPLC, FAAS, AFS, chemical sensors and biosensors
· To improve the candidates awareness of health and safety issues, including in the practical laboratory
· To describe and evaluate the principles, instrumentation, problem solving and practical aspects of atomic spectroscopy, chromatography, chemical sensors and biosensors
· To improve the students awareness of quality control in analytical chemistry
· To improve the students awareness of measurement, data handling, the use of statistics and calculations for quantitative analysis.
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| Learning Outcomes |
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On successful completion of this module you should, or should be able to:
· understand and evaluate the fundamental principles and operation of modern analytical techniques, including spectroscopy (FAAS, AFS), chromatography (GC, HPLC) and chemical sensors and biosensors in the laboratory environment;
· understand the implications of the provisions for COSHH (Control of Substances Hazardous to Health) and Health and Safety regulations in the laboratory environment;
· understand the operation of modern instrumental techniques coupled with an appreciation of instrumental calibration, sample analysis, problem solving, data handling and good laboratory practice; and
· interpret results, use appropriate equations and statistics to evaluate the data and choose methods of data presentation for reporting results.
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| Module Content |
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NIW
1-8
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Fundamentals of quality assurance and control in analytical chemistry – inter-laboratory comparisons, proficiency testing, spike recoveries, matrix-matching ; atomic absorption spectroscopy – basic instrumentation, calibration, matrix-matching, flame and electrothermal (ETV or GF) devices, interferences, background correction, hydride generation, cold vapour, practical hints and applications (absorption) spectroscopy.
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SMR
9-12
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Review basic calculations in electrochemistry amperometric biosensors, amperometry, potentiometric biosensors and applications.
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CL
13-14
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Basic principles of atomic fluorescence (AFS), instrumentation, analytical figure of merit; other ion selective electrode sensors, chemical sensors
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MB
15-18
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Statistics and data handling – F and T tests (Student and Paired), y = m x + c calibration curves; calculation of the limit of detection and quantification, applications in spectroscopy.
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DS
19-25
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Review of separation science (GC and HPLC); ion chromatography, electrophoresis and applications; sample preparation, solvent extraction, SPE, solid sample preparation, headspace, purge and trap; band spreading, Van Deemter equation, column design, qualitative and quantitative analysis, use of internal standards, applications; quality assurance and control, validation in chromatography.
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38 hours
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Practicals selected from a variety of instrumental techniques
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| Methods of Teaching/Learning |
| Combination of lectures, practical sessions |
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| Selected Texts/Journals |
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Essential:
Harris, D.C.
(2010) Quantitative Chemical Analysis, 8th Edn, Freeman
Recommended:
Fifield, F.W., Kealey, D. (2000) Principles and Practice of Analytical Chemistry, Wiley-VCH;
Allen J. Bard (2001) Electrochemical methods: fundamentals and applications - 2nd ed, John Wiley:
New York
Suggested:
Christian, G.D. (2004) Analytical Chemistry, 6th Edn, Wiley; Vandecasteele, C., Block, C.B. (1997) Modern Methods for Trace Element Determination, Wiley;
Miller, J.N., Miller, J.C., (2005) Statistics and Chemometrics for Analytical Chemistry, 5th Edn, Pearson – Prentice Hall, Harlow.
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| Last Updated |
| 21 April 2011 |
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