| Module Code: BMSM005 |
Module Title: DIET, THE GUT, FOOD ALLERGY AND INTOLERANCE |
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Module Provider: School of Biomed and Molecular Sciences
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Short Name: MOD05
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Previous Short Name: MOD05
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Level: M
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Module Co-ordinator: RAYMAN MP Prof (Bio.Science)
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Number of credits: 15
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Number of ECTS credits: 7.5
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| Module Delivery |
Short course:
11th - 13th April 2005 |
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| Assessment Requirements |
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| Module Overview |
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| Prerequisites/Co-requisites |
Contact School for details |
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| Module Aims |
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| Learning Outcomes |
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| Module Content |
- The healthy gut; digestion and absorption of macronutrients
- Areas of the gut involved in the absorption of specific micronutrients
- Adaptation of intestinal transporters
- Role of the colon in human nutrition; non-starch polysaccarides: definition and content in foods; starch and resistant starch: fermentation.
- Physiological influences of non-starch polysaccharides: plasma cholesterol lowering, modification of the glycaemic response, large bowel function, nutrient availability.
- Bacterial diversity in the GI tract; metabolic interactions; gas metabolism; proteolysis e.g. amine production; flora modulation by diet e.g. prebiotics and probiotics.
- Microflora overgrowth: candida - myth or reality?
- Acute and chronic gut infection; irritable bowel disease, colitis.
- Impaired digestion and its consequences; achlorhydria, hypochlorhydria, pancreatic exocrine hypofunction.
- Malabsorption syndromes: pathogenesis and management.
- Increased intestinal permeability; measurement of gut permeability.
- The gut and the immune system.
- Food intolerance and allergy: definitions; diagnosis; symptoms, syndromes and disease in children and adults; cows milk intolerance; atopic eczema, asthma; lactose intolerance.
- Allergy testing.
- Approaches to treatment of food intolerance: e.g. exclusion diets: use in rheumatoid arthritis etc., liabilities of exclusion diets.
- Diet and gastrointestinal disease epidemiology
- Colorectal cancer and diet: meat, non-starch polysaccharides, starch, fact, fruit and vegetables - phytoprotectants, antioxidants etc.
- Nutritional support for the gut: glutamine, dietary enzyme supplementation etc.
- Nutritional management of coeliac disease, Crohn’s disease, constipation, irritable bowel syndrome, diverticular disease, ulcerative colitis, gastrointestinal cancer (n-3 fatty acids), short-bowel syndrome.
- Prophylactic management of gut disease.
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| Last Updated |
15th August 2006 |
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