• To appreciate the mechanisms involved in the regulation of appetite and food intake and the dietary, behavioural and dietary factors which influence this

   

• To understand the role of energy expenditure and adaptive thermogenesis in the regulation of energy balance.  Introducing a range of methods for estimation of energy expenditure in humans

   

• To gain understand the metabolic regulation of the lipoprotein transport systems.  To appreciate the influence on diet on lipoprotein metabolism a, coronary disease development and the importance of nutrient-gene interaction

   

• To provide focus on the cardiovascular risk associated with the insulin resistant conditions of obesity and metabolic syndrome in relation to energy, adipose tissue and lipid metabolism

• To provide experience of laboratory techniques in the following:

   

o        Glycaemic indices of foodstuffs

o       Influence of diet composition on gut transit time and satiety

o        Use of lipid profiling in assessing CV risk

On successful completion of this module you should be able to:-

·        Demonstrate an understanding of the control of appetite and its role in regulating energy balance

·        Demonstrate an understanding of the mechanisms of adaptive thermogeneis and energy expenditure in regulating energy balance

·         Describe the integrated metabolic control of lipoprotein pathways and pathogenesis of atherosclerosis.  Appreciating the relationship between diet and coronary disease and understanding the concept of genetic susceptibility to diet

·        Demonstrate knowledge of the latest developments in obesity research and management

·        Design, plan, and undertake experiments incorporating a range of methodologies used by nutritional scientists

·        Communicate experimental findings clearly in written form with use of figure and tables where appropriate.  Discuss and critically evaluate findings in relation to the relevant literature