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| Module Availability |
| Semester One |
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| Assessment Pattern |
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Assessment:
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Examination of 90 min composed of multiple choice (weighting 20%, 40 questions) and short answers (5 out of 8 questions, weighting 40%)
Practical reports: four reports each worth 10% of the module mark
There will also be a formative MCQ during lecture 16; this will not contribute to the final module mark but it will be compulsory to attend.
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| Module Overview |
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| Prerequisites/Co-requisites |
| None |
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| Module Aims |
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· Establish a basic appreciation of cellular structures, processes and function
· Introduce modern techniques in microscopy and cellular investigations
· To provide the practical skills needed to examine cellular structure and function
· To provide an appreciation of the use of biochemical and histological skills in biomedical and clinical research laboratories
· Establish a firm basis for subsequent molecular biology, physiology and biochemistry
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| Learning Outcomes |
On successful completion of this module you should be able to:-
· Describe the intracellular components of the eukaryotic cell and relate their structure to specific functions
· Describe how DNA is organised within the nucleus and outline how access to the nucleus is controlled across the nuclear envelope
· Summarise how ribosomal subunits are manufactured
· Explain how proteins are manufactured and sent to the correct location within or outside of the cell
· Outline the role of the lysosomes in intracellular digestion and describe the various routes by which macromolecules reach them
· Explain where and how energy is produced in eukaryotic cells
· Discuss the role of the cytoskeleton in intracellular organisation and transport
· Discuss the mechanisms of cell division and cell death and briefly comment on their regulation
· Distinguish between the various images from light and electron microscopy
· Relate cellular structure to complex tissue organisation
· Examine and describe the cellular structure of organs and tissues
· Prepare / identify subcellular components of mammalian cells
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| Module Content |
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Lecture
Number
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Staff
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Topic
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1
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KEP
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Introduction to the module aims and learning objectives
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2
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KEP
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Organelles 1: the nucleus, structure, organisation 1
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3
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KEP
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Organelles 2: the nucleus, structure, organisation 2
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4
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KEP
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Organelles 3: the nucleus, structure, organisation 3
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5
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KEP
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Organelles 4: ribosomes
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6
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KEP
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Organelles 5: endoplasmic reticulum and the Golgi apparatus – 1
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7
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KEP
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Organelles 6: endoplasmic reticulum and the Golgi apparatus – 2
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8
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KEP
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Exocytosis and endocytosis
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9
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KEP
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Organelles 7: lysosomes and peroxisomes
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10
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KEP
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Organelles 8: mitochondria
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11
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KEP
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Organelles 9: mitochondrial proteins plus introduction to the cytoskeleton
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12
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KEP
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Organelles 10: cytoskeleton and mobility in eukaryotes
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13
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KEP
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Mitosis
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14
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KEP
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Meiosis
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15
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KEP
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Apoptosis
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16
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KEP
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Formative MCQ on lectures 1-12 (30 minutes)
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17
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JAH?
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Visualising tissues and cells
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18
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JAH?
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Tissues 1: epithelial tissue 1
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19
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JAH?
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Tissues 2: epithelial tissue 2
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20
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KEP
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Tutorial for Part 1 of the module (Cell organelles) and MCQ feedback
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21
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KEP?
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Tissues 3: connective tissue 1
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22
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KEP?
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Tissues 4: connective tissue 2
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23
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SNA?
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Tissues 5: muscle
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24
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SNA?
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Tissues 6: nerve
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25
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JAH?
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Tissues 7: blood
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26
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KEP?
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Junctions between cells
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| Methods of Teaching/Learning |
| Lectures, practicals and tutorials |
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| Selected Texts/Journals |
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Recommended Textbooks:
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Alberts B, et al. (2008) Molecular Biology of the Cell, 5th Edition, Garland Publishing (also recommended for Molecular Biology module)
OR: Cooper, G M and Hausman, R E (2007) The Cell: Molecular Approach, 5th Edition, ASM Press
Alternatively: Alberts et al (2004) Essential Cell Biology (2nd Ed,
Garland ) is simpler but may not contain enough detail for those doing cell/molecular biology at level 3
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Also consult:
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Wilson & Hunt (2002) Molecular Biology of the Cell: A Problems Approach
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Norman R L and Lodwick, D (2007) Flesh and Bones of Medical Cell Biology, Elsevier:
A basic introduction to cell biology
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Bradbury S and Bracegirdle B (1998) Introduction to Light Microscopy, Bios
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Oldfield L J (1993) Light Microscopy - An Illustrated Guide, Mosby-Wolfe
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Young B, Lowe JS, Stevens A and Heath J (2006) Wheater’s Functional Histology, 5th Edition, Churchill Livingstone
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Graham J and Rickwood D (ed) (1997) Subcellular Fractionation - A Practical Approach, IRL Press
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| Last Updated |
| 5 April 2011 |
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